Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162567 | 0.83 | TSHR (0.54) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL758937 | 0.83 | TSHR (0.58) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL5161528 | 0.83 | TSHR (0.54) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL16223395 | 0.83 | TSHR (0.58) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL16223438 | 0.83 | TSHR (0.58) | TSHRNPSR1PRCPGAAOPRM1 | |
| Bromide SCHEMBL9255826 | 0.81 | TSHR (0.51) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL30519196 | 0.76 | OPRM1 (0.54) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL27442086 | 0.74 | IDO1 (0.53) | TSHROPRM1MAPT | |
| SCHEMBL327054 | 0.73 | PRCP (0.56) | TSHRNPSR1PRCPGAAOPRM1 | |
| SCHEMBL31062461 | 0.73 | PRCP (0.56) | TSHRNPSR1PRCPGAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438348-A | The preparation method and preparation method thereof of one kind (S) -1- phenyl -1,2,3,4- tetrahydroisoquinoline | 凯瑞斯德生化(苏州)有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-103159677-B | The preparation method of IQL | Ji'nan Healtang Biotechnology Co., Ltd. (CN) | 2016-03-16 | — | — | CN | disclosed |
| CN-103159677-A | 1-phenyl-1, 2, 3, 4-tetrahydroisoquinoline preparation method | JINAN SHENGQUAN HEALTANG BIOLOG TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | disclosed |