SCHEMBL27908366

SCHEMBL27908366

[Ir].c1ccc2cc(-c3cc(-c4ccc5ccccc5c4)ncn3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.58
CYP1A1 P04798 1/20 0.55
CYP1B1 Q16678 1/20 0.55
SMN1; SMN2 Q16637 5/20 0.50
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
MAPT P10636 3/20 0.50
AR P10275 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
CYP2C19 P33261 1/20 0.50
NFKB1 P19838 1/20 0.50
GFER P55789 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
CYP11B1 P15538 2/20 0.46
CYP11B2 P19099 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126907 0.98 CYP1A2 (0.60) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL18731739 0.92 CYP1A1 (0.66) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL14725249 0.90 CYP1A1 (0.54) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL23008424 0.90 CYP1A1 (0.64) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL14725255 0.88 CYP1A2 (0.50) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL27926508 0.88 CYP1A2 (0.47) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL27882854 0.87 CTRC (0.57) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL30595382 0.86 CYP1A1 (0.59) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL25841458 0.86 CYP1A1 (0.59) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL27908371 0.86 CYP1A2 (0.49) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103168043-A Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-06-19 CN disclosed