SCHEMBL2126907

SCHEMBL2126907

c1ccc2cc(-c3cc(-c4ccc5ccccc5c4)ncn3)ccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.60
CYP1A1 P04798 1/20 0.56
CYP1B1 Q16678 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.52
ALDH1A1 P00352 3/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
KDM4E B2RXH2 2/20 0.52
AR P10275 2/20 0.52
MAPT P10636 2/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
NFKB1 P19838 1/20 0.52
GFER P55789 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
CYP11B1 P15538 2/20 0.47
CYP11B2 P19099 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27908366 0.98 CYP1A2 (0.58) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL18731739 0.94 CYP1A1 (0.66) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL23008424 0.92 CYP1A1 (0.64) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL14725249 0.92 CYP1A1 (0.54) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL14725255 0.90 CYP1A2 (0.50) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL27882854 0.89 CTRC (0.57) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL30595382 0.88 CYP1A1 (0.59) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL25841458 0.88 CYP1A1 (0.59) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL27908371 0.88 CYP1A2 (0.49) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1
SCHEMBL2127352 0.87 CYP1A2 (0.47) CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-06-17 US disclosed
US-12331065-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-06-17 US disclosed
US-20220402954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-22 US disclosed
US-20220106344-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-07 US disclosed
US-20210098717-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
US-20210098717-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-9985223-B2 Iridium organometallic complexes comprising 4-arylpyrimidines SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-29 US disclosed
US-20160064678-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-03 US disclosed
US-20150108462-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2015-04-23 US disclosed
US-8921548-B2 4-arylpyrimidine derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-30 US disclosed
US-8921548-B2 4-arylpyrimidine derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-30 US disclosed
US-8921548-B2 4-arylpyrimidine derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-30 US disclosed
CN-103168043-A Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-06-19 CN disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-26 US disclosed
WO-2012053627-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-04-26 WO disclosed
WO-2012053627-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CTCF, CCNY, RUVBL2 CYP1A2 908/4885CYP1A1 582/4885CYP1B1 1157/4885
US-20120098417-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device NR2E3, IGF1R, GRIA1 CYP1A2 473/4885CYP1A1 48/4885CYP1B1 284/4885
US-12331237-B2 Organic electroluminescent materials and devices CTCF, RUVBL2, RUVBL1 CYP1A2 701/4885CYP1A1 488/4885CYP1B1 859/4885
US-12331065-B2 Organic electroluminescent materials and devices CTCF, CCNY, RUVBL2 CYP1A2 908/4885CYP1A1 582/4885CYP1B1 1157/4885
US-20220106344-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CTCF, CCNY, RUVBL2 CYP1A2 908/4885CYP1A1 582/4885CYP1B1 1157/4885
US-20210098717-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CTCF, RUVBL2, RUVBL1 CYP1A2 701/4885CYP1A1 488/4885CYP1B1 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.