Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140819 | 0.78 | PDE2A (0.42) | MEN1KMT2ACES2KDM4EHSD17B10 | |
| SCHEMBL3033286 | 0.78 | PDE2A (0.39) | MEN1KMT2ACES2MAPTKDM4E | |
| SCHEMBL2703782 | 0.78 | CES2 (0.50) | CES2AR | |
| SCHEMBL3032872 | 0.76 | MRGPRX4 (0.47) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL13464023 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2ACES2KDM4EALDH1A1 | |
| SCHEMBL483405 | 0.73 | IDO1 (0.41) | MEN1KMT2ACES2TSHRKDM4E | |
| SCHEMBL6387748 | 0.73 | CES2 (0.50) | MEN1KMT2ACES2TSHRKDM4E | |
| SCHEMBL187014 | 0.73 | NQO2 (0.61) | MEN1KMT2ACES2HSP90AA1MAPT | |
| SCHEMBL14307167 | 0.72 | MEN1 (0.44) | MEN1KMT2ACES2HSP90AA1MAPT | |
| SCHEMBL2515789 | 0.72 | PTGDR2 (0.43) | MEN1KMT2ACYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145662-A | N-substituted animobutyrolactone derivatives and uses thereof | SHENZHEN WANHE PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-103145662-B | N-substituted animobutyrolactone derivatives and uses thereof | SHENZHEN WANHE PHARMACEUTICAL CO LTD | 2014-07-16 | — | — | CN | disclosed |
| CN-103145662-A | N-substituted animobutyrolactone derivatives and uses thereof | SHENZHEN WANHE PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | disclosed |