Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909268 | 0.86 | RECQL (0.51) | RECQLHSP90AA1CCR6TDP1POLB | |
| SCHEMBL3424022 | 0.85 | ALDH1A1 (0.43) | RECQLTDP1POLBGAAALDH1A1 | |
| SCHEMBL3644238 | 0.79 | ALDH1A1 (0.43) | TDP1POLBKDM4EALDH1A1MAPK1 | |
| SCHEMBL2473570 | 0.77 | ALDH1A1 (0.41) | TDP1POLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15929085 | 0.76 | MAPT (0.36) | TDP1POLBKDM4EALDH1A1MAPK1 | |
| SCHEMBL2590559 | 0.76 | CYP1A2 (0.43) | CCR6TDP1POLBALDH1A1MAPK1 | |
| SCHEMBL3678417 | 0.75 | F2RL3 (0.36) | GAAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2471712 | 0.75 | RAB9A (0.38) | TDP1POLBKDM4EGAAALDH1A1 | |
| SCHEMBL12179486 | 0.74 | ALDH1A1 (0.39) | KDM4EGAAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8088675 | 0.74 | RECQL (0.44) | RECQLHSP90AA1CCR6TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906071-A | Method for producing substituted pyridin-2-one | Bayer Pharma AG | 2013-01-30 | — | — | CN | disclosed |