Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 6/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792960 | 0.90 | NAMPT (0.53) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2792181 | 0.90 | ROCK2 (0.51) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2793989 | 0.90 | NAMPT (0.55) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2793307 | 0.90 | NT5E (0.55) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2790576 | 0.90 | RAB9A (0.54) | RAB9ASMN1; SMN2NAMPTROCK2ROCK1 | |
| SCHEMBL2792068 | 0.90 | NAMPT (0.60) | RAB9ASMN1; SMN2NAMPTROCK2ROCK1 | |
| SCHEMBL2794919 | 0.89 | HIF1A (0.52) | NAMPTROCK2ROCK1KDM4EL3MBTL1 | |
| SCHEMBL2793459 | 0.86 | ROCK2 (0.61) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2790105 | 0.85 | HDAC1 (0.51) | RAB9ANPC1SMN1; SMN2NAMPTROCK2 | |
| SCHEMBL2792457 | 0.85 | MEN1 (0.59) | RAB9ANAMPTROCK2ROCK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168102-A9 | Amide Derivatives as Kinase Inhibitors | DEVGEN NV (BE) | 2010-07-01 | — | — | US | disclosed |
| US-20090118283-A1 | Amide Derivatives as Kinase Inhibitors | DEVGEN NV (BE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168102-A9 | Amide Derivatives as Kinase Inhibitors | MAP3K1, CDK1, CDK2 | RAB9A 2781/4885NPC1 1738/4885SMN1; SMN2 3334/4885 |
| US-20090118283-A1 | Amide Derivatives as Kinase Inhibitors | MAP3K1, CDK1, CDK2 | RAB9A 2781/4885NPC1 1738/4885SMN1; SMN2 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.