Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909415 | 0.85 | MAPT (0.43) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL27892282 | 0.84 | MAPT (0.42) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL9982680 | 0.78 | C5AR1 (0.49) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL27892283 | 0.72 | SLC6A2 (0.41) | LMNAALDH1A1OPRM1KDM4EPLA2G1B | |
| SCHEMBL3536097 | 0.71 | LMNA (0.73) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL30784585 | 0.70 | MAPT (0.72) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL3534109 | 0.70 | LMNA (0.71) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL2041681 | 0.70 | MAPT (0.79) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL5093165 | 0.68 | POLB (1.00) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL27909414 | 0.67 | LMNA (0.52) | MAPTL3MBTL1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947275-A | Piperidinyl-substituted 1, 3-dihydro-benzimidazol-2-ylideneamine derivatives | NOVARTIS AG | 2013-02-27 | — | — | CN | disclosed |