Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GOT1 | P17174 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909302 | 0.85 | MAPT (0.52) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL27892282 | 0.84 | MAPT (0.42) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL9982895 | 0.81 | C5AR1 (0.42) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL27909350 | 0.75 | OPRM1 (0.43) | MAPTOPRM1OPRK1OPRL1GAA | |
| SCHEMBL30784585 | 0.67 | MAPT (0.72) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL3536097 | 0.66 | LMNA (0.73) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL9982413 | 0.66 | C5AR1 (0.43) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL9982680 | 0.65 | C5AR1 (0.49) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL3534109 | 0.65 | LMNA (0.71) | MAPTL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL9982900 | 0.64 | GOT1 (0.41) | MAPTOPRM1OPRK1OPRL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947275-A | Piperidinyl-substituted 1, 3-dihydro-benzimidazol-2-ylideneamine derivatives | NOVARTIS AG | 2013-02-27 | — | — | CN | disclosed |