Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252929 | 0.94 | MEN1 (0.38) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Sulfuric Acid SCHEMBL27725114 | 0.94 | MEN1 (0.41) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL1476595 | 0.93 | MEN1 (0.45) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL166563 | 0.93 | MEN1 (0.45) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Sulfuric Acid SCHEMBL6476110 | 0.93 | MEN1 (0.45) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Bromide SCHEMBL2250534 | 0.92 | MEN1 (0.44) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Iodide SCHEMBL2252213 | 0.92 | MEN1 (0.44) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Fluoride Ion SCHEMBL14815797 | 0.92 | MEN1 (0.44) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Methacrylic Acid SCHEMBL9489875 | 0.91 | MEN1 (0.41) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Methacrylic Acid SCHEMBL9487522 | 0.91 | MEN1 (0.41) | MEN1KMT2ATP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490142-B | Use of composite materials based on carbon nanotubes as thickening agents for aqueous solutions | ARKEMA FRANCE | 2013-06-19 | — | — | CN | claimed |
| US-20120132843-A1 | USE OF COMPOSITE MATERIALS BASED ON CARBON NANOTUBES AS THICKENING AGENTS FOR AQUEOUS SOLUTIONS | C.N.R.S. (FR) | 2012-05-31 | — | — | US | claimed |
| US-7772340-B2 | Alkoxyamines originating from β-phoshorated nitroxides and use thereof in radical polymerisation | ARKEMA FRANCE (FR) | 2010-08-10 | — | — | US | claimed |
| US-7635740-B2 | Method for radical emulsion polymerisation using hydrosoluble alkoxyamines | ARKEMA FRANCE (FR) | 2009-12-22 | — | — | US | claimed |
| CN-101490142-A | Use of composite materials based on carbon nanotubes as thickening agents for aqueous solutions | ARKEMA FRANCE (FR) | 2009-07-22 | — | — | CN | claimed |
| US-20070123669-A1 | Method for radical emulsion polymerisation using hydrosoluble alkoxyamines | ARKEMA FRANCE (FR) | 2007-05-31 | — | — | US | claimed |
| CN-101490142-B | Use of composite materials based on carbon nanotubes as thickening agents for aqueous solutions | ARKEMA FRANCE | 2013-06-19 | — | — | CN | disclosed |
| US-20100168338-A1 | METHOD FOR PREPARING A POLYMERIC MATERIAL INCLUDING A MULTIBLOCK COPOLYMER PREPARED BY CONTROLLED FREE-RADICAL POLYMERISATION | ARKEMA FRANCE (FR) | 2010-07-01 | — | — | US | disclosed |
| CN-101490142-A | Use of composite materials based on carbon nanotubes as thickening agents for aqueous solutions | ARKEMA FRANCE (FR) | 2009-07-22 | — | — | CN | disclosed |
| CN-101405338-A | Use of particular polymers or copolymers as surfactants for stabilizing latices | ARKEMA FRANCE (FR) | 2009-04-08 | — | — | CN | disclosed |
| CN-101365732-A | Method for preparing a polymeric material including a multiblock copolymer prepared by controlled free-radical polymerisation | ARKEMA FRANCE (FR) | 2009-02-11 | — | — | CN | disclosed |
| CN-101336267-A | Pulverulent composition based on carbon nanotubes, methods of obtaining them and its uses, especially in polymeric materials | ARKEMA FRANCE (FR) | 2008-12-31 | — | — | CN | disclosed |
| WO-2005075531-A1 | AMPHIPHILIC BLOCK AND GRAFT COPOLYMERS CONTAINING HEAVY ELEMENTS, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS X-RAY CONTRAST AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-08-18 | — | — | WO | disclosed |