Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917382 | 0.94 | MEN1 (0.50) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL3899764 | 0.94 | MEN1 (0.50) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Sulfuric Acid SCHEMBL2790955 | 0.93 | MEN1 (0.40) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Iodide SCHEMBL14815831 | 0.92 | MEN1 (0.49) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Fluoride Ion SCHEMBL14815193 | 0.92 | MEN1 (0.49) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Bromide SCHEMBL14815540 | 0.92 | MEN1 (0.49) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL14815769 | 0.90 | MEN1 (0.52) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL10301520 | 0.89 | MEN1 (0.55) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Bromide SCHEMBL14815770 | 0.89 | MEN1 (0.51) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Fluoride Ion SCHEMBL14815771 | 0.89 | MEN1 (0.51) | MEN1KMT2ATP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075531-A1 | AMPHIPHILIC BLOCK AND GRAFT COPOLYMERS CONTAINING HEAVY ELEMENTS, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS X-RAY CONTRAST AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-08-18 | — | — | WO | disclosed |