Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 1.00 |
| ▸ | DRD2 | P14416 | 16/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909555 | 0.94 | HTR1A (0.88) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL4194997 | 0.94 | HTR1A (1.00) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL27860653 | 0.92 | HTR1A (0.85) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL4336592 | 0.90 | HTR1A (0.82) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL13944275 | 0.90 | HTR1A (0.80) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL11313868 | 0.86 | HTR1A (0.75) | HTR1ADRD2HTR2ASLC6A4DRD1 | |
| SCHEMBL11786344 | 0.85 | HTR1A (0.85) | HTR1ADRD2HTR2ADRD1DRD3 | |
| SCHEMBL7649906 | 0.82 | HTR1A (0.83) | HTR1ADRD2HTR2AOPRM1OPRK1 | |
| SCHEMBL7704740 | 0.82 | SLC6A4 (1.00) | HTR1ADRD2SLC6A4 | |
| SCHEMBL8553783 | 0.81 | HTR1A (0.81) | HTR1ADRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276581-B | N-substituted tetrahydropyridine bound indole compound as well as preparation method and application thereof | UNIV SHANGHAI | 2013-06-12 | — | — | CN | disclosed |