Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631746 | 0.82 | MAPT (0.50) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL456414 | 0.82 | MAPT (0.50) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL4745533 | 0.80 | MAPT (0.48) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL29922677 | 0.80 | MAPT (0.48) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL94041 | 0.80 | FCGR3B (0.51) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL12352580 | 0.78 | MAPT (0.52) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL11472336 | 0.78 | FCGR3B (0.50) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL22631192 | 0.78 | MAPT (0.47) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL10994687 | 0.78 | EGFR (0.57) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL10866261 | 0.77 | DDX3X (0.47) | MAPTKDM4EMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193722-A | Novel quinazoline nitrogen mustard compound, and preparation method and application thereof to treatment of cancer | UNIV BEIJING NORMAL | 2013-07-10 | — | — | CN | disclosed |