Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27927859 | 0.83 | ALDH1A1 (0.74) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27910126 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL24279540 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27910290 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27927862 | 0.80 | HTT (0.69) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27927814 | 0.80 | ALDH1A1 (0.65) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL24279539 | 0.79 | RORC (0.70) | ALDH1A1HPGDHTTMAPT | |
| SCHEMBL27910212 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27927811 | 0.77 | ALDH1A1 (0.66) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27927883 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193691-A | Sulfonamide compound and medicinal compositions thereof, and preparation methods and applications thereof | SHANGHAI INST MATERIA MEDICA | 2013-07-10 | — | — | CN | claimed |
| CN-103193691-A | Sulfonamide compound and medicinal compositions thereof, and preparation methods and applications thereof | SHANGHAI INST MATERIA MEDICA | 2013-07-10 | — | — | CN | disclosed |