Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | F2R | P25116 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824437 | 0.83 | HDAC3 (0.69) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL6658490 | 0.83 | MAPK1 (0.69) | MAPK1ALDH1A1LMNAPOLBGAA | |
| SCHEMBL7935540 | 0.82 | MAPT (0.47) | MAPK1ALDH1A1LMNAPOLBHDAC3 | |
| SCHEMBL25063197 | 0.81 | MAPK1 (0.54) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL14229246 | 0.81 | MAPK1 (0.57) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL9686302 | 0.81 | MAPK1 (0.57) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL14229281 | 0.79 | MAPK1 (0.55) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL12284937 | 0.79 | ALDH1A1 (0.69) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL12265589 | 0.79 | ALDH1A1 (0.56) | MAPK1ALDH1A1MEN1LMNATHRA | |
| SCHEMBL25063201 | 0.79 | ALDH1A1 (0.56) | MAPK1ALDH1A1MEN1LMNATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101378742-B | Use of KCNQ-openers for the preparation of a pharmaceutical composition for the treatment of schizophrenia | LUNDBECK & CO AS H | 2013-07-10 | — | — | CN | disclosed |