Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996347 | 0.82 | HPGD (0.66) | MAPTALDH1A1HSD17B10HPGDALOX12 | |
| SCHEMBL27910331 | 0.82 | MAPK1 (0.57) | MAPTALDH1A1MAPK1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL28755176 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HSD17B10HPGDMAPK1HDAC3 | |
| SCHEMBL12354757 | 0.76 | LMNA (0.48) | MAPTALDH1A1HSD17B10HPGDALOX12 | |
| SCHEMBL7924678 | 0.75 | HSD17B10 (0.46) | MAPTALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3232190 | 0.74 | HDAC1 (0.72) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22973017 | 0.73 | CDC25B (0.49) | MAPTALDH1A1HSD17B10HPGDHDAC3 | |
| SCHEMBL17931860 | 0.73 | TGM2 (0.46) | ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL1509787 | 0.72 | ALDH1A1 (0.51) | MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7924727 | 0.72 | ALDH1A1 (0.46) | MAPTALDH1A1HSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033360-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | 1/3 ABSOLUTE SCIENCE, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2009045761-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | ABSOLUTE SCIENCE, INC. (US) | 2009-04-09 | — | — | WO | disclosed |