Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655987 | 0.84 | KDM4E (0.53) | ALDH1A1SMN1; SMN2TRPV1GRM1GRM5 | |
| SCHEMBL6649430 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TRPV1GRM1GRM5 | |
| SCHEMBL73964 | 0.82 | GRM5 (0.60) | GRM1GRM5TNK2 | |
| SCHEMBL1458888 | 0.81 | TRPV1 (0.59) | ALDH1A1SMN1; SMN2TRPV1GRM1GRM5 | |
| SCHEMBL2078087 | 0.81 | CDK9 (0.41) | ALDH1A1SMN1; SMN2TRPV1MEN1KMT2A | |
| SCHEMBL27911620 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TRPV1GRM5MEN1 | |
| SCHEMBL10317879 | 0.78 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TRPV1MEN1KMT2A | |
| SCHEMBL6353439 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TRPV1TNK2MEN1 | |
| SCHEMBL26132375 | 0.76 | LIMK1 (0.37) | ALDH1A1SMN1; SMN2TRPV1TNK2LIMK1 | |
| SCHEMBL27929255 | 0.76 | TRPV1 (0.41) | TRPV1LIMK1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214460-A | Chemical compounds | SYNGENTA PARTICIPATIONS AG | 2013-07-24 | — | — | CN | disclosed |