Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789066 | 0.94 | SCN9A (0.35) | SCN9ADPP4PROKR1NMT2NMT1 | |
| SCHEMBL2791979 | 0.89 | PROKR1 (0.43) | SCN9ADPP4PROKR1NMT2NMT1 | |
| SCHEMBL2789639 | 0.83 | PROKR1 (0.42) | SCN9ADPP4PROKR1GRIN2BKMT2A | |
| SCHEMBL2788438 | 0.78 | CFD (0.33) | SCN9ADPP4PROKR1DPP7KMT2A | |
| SCHEMBL2789934 | 0.78 | DPP4 (0.34) | SCN9ADPP4KMT2A | |
| SCHEMBL2788501 | 0.78 | ALDH1A1 (0.32) | DPP4PROKR1DPP7KMT2A | |
| SCHEMBL2792314 | 0.77 | PROKR1 (0.43) | DPP4PROKR1KMT2ACFD | |
| SCHEMBL2813649 | 0.77 | PROKR1 (0.44) | DPP4PROKR1KMT2ACFD | |
| SCHEMBL2816909 | 0.75 | PROKR1 (0.42) | DPP4PROKR1KMT2ACFD | |
| SCHEMBL2818318 | 0.75 | PROKR1 (0.42) | DPP4PROKR1KMT2ACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |