Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930289 | 0.95 | FYN (0.51) | FYNCHEK2TGFBR1ACVR1PDGFRB | |
| SCHEMBL27930286 | 0.89 | MAPT (0.44) | FYNTGFBR1ACVR1KITGAA | |
| SCHEMBL27930349 | 0.86 | TGFBR1 (0.47) | FYNTGFBR1ACVR1KITGAA | |
| SCHEMBL27912261 | 0.85 | TUBB4A (0.52) | FYNTGFBR1ACVR1MAPTALDH1A1 | |
| SCHEMBL27912273 | 0.84 | MAPT (0.46) | FYNTGFBR1ACVR1PDGFRBMAPT | |
| SCHEMBL27930273 | 0.83 | MGAM (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28117798 | 0.82 | FYN (0.55) | FYNCHEK2TGFBR1PDGFRBKIT | |
| SCHEMBL27912262 | 0.80 | TUBB4A (0.55) | FYNTGFBR1ACVR1MAPTALDH1A1 | |
| SCHEMBL27912270 | 0.80 | KDM4E (0.45) | FYNTGFBR1ACVR1PDGFRBMAPT | |
| SCHEMBL27912265 | 0.78 | MGAM (0.48) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103183640-B | Diaryl pyrazole azole compounds and preparation method thereof and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-103183640-A | Diaryl pyrazole compound, and preparation method and purpose thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-07-03 | — | — | CN | disclosed |