SCHEMBL27913022

SCHEMBL27913022

BrCC=C(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.44
CES2 O00748 2/20 0.44
AKR1B1 P15121 1/20 0.44
TSHR P16473 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TRPA1 O75762 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
BTN3A1 O00481 1/20 0.38
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
MAOB P27338 1/20 0.37
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CTBP2 P56545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631890 0.79 MAOB (0.50) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL11277665 0.79 CES1 (0.46) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL11200646 0.78 CES1 (0.41) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL28806825 0.78 CES1 (0.41) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL11200644 0.78 CES1 (0.41) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL8668128 0.77 CES1 (0.44) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL516676 0.77 CES1 (0.44) CES1CES2AKR1B1TSHRMEN1
SCHEMBL15302703 0.77 CES1 (0.40) CES1CES2AKR1B1TSHRALDH1A1
Bromide SCHEMBL11619427 0.76 CES1 (0.43) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL9504972 0.76 CES1 (0.43) CES1CES2AKR1B1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103249762-A Addition-curable metallosiloxane compound DAICEL CORP 2013-08-14 CN disclosed