Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310293 | 0.86 | CES1 (0.50) | CES1CES2AKR1B1TSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27571740 | 0.84 | CES1 (0.48) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL8166684 | 0.77 | ALDH1A1 (0.50) | CES1CES2AKR1B1ALDH1A1TDP1 | |
| SCHEMBL27913022 | 0.76 | CES1 (0.44) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL27913000 | 0.74 | CES2 (0.39) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL16795637 | 0.73 | CES1 (0.46) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL27913019 | 0.73 | CES1 (0.46) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL9702035 | 0.72 | CES1 (0.50) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL27912978 | 0.71 | CES1 (0.40) | CES1CES2AKR1B1TSHRALDH1A1 | |
| SCHEMBL516687 | 0.70 | CES1 (0.48) | CES1CES2AKR1B1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556405-A1 | PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY | Japan Tobacco Inc. (JP) | 1993-08-25 | — | — | EP | disclosed |