Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27706169 | 0.85 | PDE10A (0.58) | PDE10AMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8764374 | 0.79 | CYSLTR1 (0.46) | PDE10ACYP1A2CYP2C9 | |
| SCHEMBL12066225 | 0.78 | PDE10A (1.00) | PDE10AMAPTMEN1KMT2A | |
| Water SCHEMBL27574375 | 0.77 | CYSLTR1 (0.45) | PDE10ACYP1A2CYP2C9 | |
| SCHEMBL7317271 | 0.75 | PDE10A (0.77) | PDE10AMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL27490996 | 0.75 | HDAC3 (0.46) | PDE10AKMT2ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL27525389 | 0.75 | PDE10A (0.59) | PDE10AMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL28689056 | 0.74 | L3MBTL1 (0.49) | PDE10ACYP1A2NPC1RAB9AL3MBTL1 | |
| SCHEMBL6265020 | 0.74 | PDE10A (0.62) | PDE10AMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL27863137 | 0.73 | ALDH1A1 (0.36) | PDE10AMAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242250-A | Preparation method of 2-quinoxaline methylene hydrazino cyanoacetic acid-N1-oxide | UNIV CHINA AGRICULTURAL | 2013-08-14 | — | — | CN | disclosed |