Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931361 | 0.82 | GCGR (0.39) | NR2E1GCGRMRGPRX4P2RY14 | |
| SCHEMBL27931358 | 0.81 | HCAR2 (0.41) | NR2E1GCGRHCAR2 | |
| SCHEMBL27913342 | 0.81 | MEN1 (0.47) | SYKNR2E1MRGPRX4 | |
| SCHEMBL28371862 | 0.80 | GCGR (0.47) | GCGR | |
| SCHEMBL24526678 | 0.77 | TTR (0.39) | HCAR1TTRNR2E1HCAR2 | |
| SCHEMBL28660386 | 0.76 | TTR (0.39) | HCAR1TTRHCAR2P2RY14 | |
| SCHEMBL31133385 | 0.76 | HCAR1 (0.48) | HCAR1TTRHCAR2 | |
| SCHEMBL21816143 | 0.76 | HCAR1 (0.48) | HCAR1TTRHCAR2 | |
| SCHEMBL396514 | 0.74 | NR2E1 (0.64) | NR2E1 | |
| SCHEMBL29874680 | 0.74 | NR2E1 (0.64) | NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221047-A | Compounds and methods | TEMPERO PHARMACEUTICALS INC | 2013-07-24 | — | — | CN | disclosed |