Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457706 | 0.89 | GPBAR1 (0.59) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL2475844 | 0.89 | GPBAR1 (0.59) | GPBAR1LMNAKMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL3981907 | 0.87 | GPBAR1 (0.57) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL3068021 | 0.87 | GPBAR1 (0.61) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL4718673 | 0.87 | KMT2A (0.72) | GPBAR1LMNAKMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL30684627 | 0.86 | KMT2A (0.70) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL17736156 | 0.85 | GPBAR1 (0.57) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL8408128 | 0.84 | ALDH1A1 (0.60) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL4721200 | 0.84 | LMNA (0.72) | GPBAR1LMNAKMT2AGAAMEN1 | |
| SCHEMBL2471701 | 0.83 | GPBAR1 (0.54) | GPBAR1LMNAKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201268-A | Novel piperazine analogs as broad-spectrum influenza antivirals | BRISTOL MYERS SQUIBB CO | 2013-07-10 | — | — | CN | disclosed |