SCHEMBL27914704

SCHEMBL27914704

NC(=O)c1ccc(-c2cccnc2-c2ccc(C(N)=O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MKNK1 Q9BUB5 8/20 0.71
▸ MKNK2 Q9HBH9 8/20 0.71
▸ CAMKK2 Q96RR4 1/20 0.56
▸ CHEK2 O96017 5/20 0.49
▸ RIPK1 Q13546 1/20 0.49
▸ PTGS1 P23219 1/20 0.49
▸ PTGS2 P35354 1/20 0.49
▸ IKBKB O14920 1/20 0.47
▸ CHUK O15111 1/20 0.47
▸ TGFBR1 P36897 2/20 0.44
▸ CDC7 O00311 1/20 0.43
▸ PLK4 O00444 1/20 0.43
▸ CHEK1 O14757 1/20 0.43
▸ MAPK13 O15264 1/20 0.43
▸ PDPK1 O15530 1/20 0.43
▸ DAPK3 O43293 1/20 0.43
▸ DYRK3 O43781 1/20 0.43
▸ ROCK2 O75116 1/20 0.43
▸ PRKD3 O94806 1/20 0.43
▸ MAP4K4 O95819 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28226910 0.83 MKNK1 (0.76) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL15730267 0.81 MKNK1 (1.00) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL14422898 0.81 PTGS1 (0.59) MKNK1MKNK2CAMKK2PTGS1PTGS2
SCHEMBL14430022 0.79 MKNK1 (0.53) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL14555428 0.79 MKNK1 (0.68) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL6070469 0.79 MKNK2 (0.65) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL20371520 0.78 MKNK1 (0.66) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL17815694 0.78 MKNK1 (0.63) MKNK1MKNK2CAMKK2CHEK2RIPK1
SCHEMBL14639086 0.78 TRPV1 (0.62) MKNK1MKNK2
SCHEMBL10094509 0.78 MKNK1 (0.54) MKNK1MKNK2CAMKK2CHEK2RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993748-A Polyimide film and method for preparing double-layer flexible copper-clad plate by utilizing same UNIV NANJING SCIENCE & TECH 2013-03-27 — — CN claimed
CN-102993748-B Polyimide film and method for preparing double-layer flexible copper-clad plate by utilizing same NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2014-10-08 — — CN disclosed
CN-102993748-A Polyimide film and method for preparing double-layer flexible copper-clad plate by utilizing same UNIV NANJING SCIENCE & TECH 2013-03-27 — — CN disclosed
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