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Sugi Predict / Compounds / SCHEMBL279156

SCHEMBL279156

SCHEMBL279156

Cc1cc(-c2ccc(N(c3ccc(C=C(c4ccccc4)c4ccccc4)cc3)c3ccc(C4CO4)cc3)c(C)c2)ccc1N(c1ccc(C=C(c2ccccc2)c2ccccc2)cc1)c1ccc(C2CO2)cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 2/20 0.34
▸ PTGS2 P35354 5/20 0.34
▸ TSHR P16473 1/20 0.33
▸ CYP19A1 P11511 1/20 0.32
▸ CYP11B2 P19099 1/20 0.32
▸ ESR1 P03372 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ CHRM4 P08173 1/20 0.30
▸ CHRM1 P11229 1/20 0.30
▸ CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278979 0.84 TSHR (0.44) PTGS2TSHRCYP19A1CYP11B2ESR1
SCHEMBL15478868 0.79 PTGS2 (0.44) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL13991014 0.78 PDE4A (0.30) —
SCHEMBL10057475 0.78 PTGS2 (0.47) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL13681231 0.77 CYP2D6 (0.35) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL19795461 0.77 PTGS2 (0.49) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL25053712 0.77 PTGS2 (0.41) PTGS2CYP19A1CYP11B2ESR1ALDH1A1
SCHEMBL13679130 0.76 PTGS2 (0.35) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL14769858 0.76 PTGS2 (0.51) PTGS2CYP19A1CYP11B2ESR1CYP2D6
SCHEMBL13050002 0.76 PTGS2 (0.51) PTGS2CYP19A1CYP11B2ESR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 — — US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 — — US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed