Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584512 | 0.87 | LMNA (0.48) | KAT6AKDM4ELMNAKDM5AKDM2B | |
| SCHEMBL28146277 | 0.85 | MAPT (0.49) | KAT6AKDM4ELMNAKDM5AKDM2B | |
| SCHEMBL1645251 | 0.83 | LMNA (0.52) | KAT6AKDM4ELMNAKDM5AKDM2B | |
| SCHEMBL20462873 | 0.81 | KAT6A (0.54) | KAT6ALMNAKDM5AKDM2BKDM4C | |
| SCHEMBL3665773 | 0.81 | NOTUM (0.53) | KDM4ENPC1LMNAMAPT | |
| SCHEMBL27933790 | 0.79 | DGAT1 (0.44) | KAT6ALMNAKDM5AKDM2BKDM4C | |
| Naphthalene SCHEMBL27658466 | 0.76 | TPMT (0.67) | CTRCNPC1TPMT | |
| SCHEMBL27569832 | 0.75 | NPC1 (0.53) | CTRCKDM4ENPC1MAPT | |
| SCHEMBL321724 | 0.73 | LMNA (0.61) | KDM4ELMNAKDM5AKDM2BKDM4C | |
| SCHEMBL1285806 | 0.73 | MAPT (0.57) | KAT6AKDM4ELMNAMAPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261192-A | 5-methyl-1-(naphthalen--yl)-1h-pyrazole derivatives and their use in potentiating the effect of opioid analgesics | ESTEVE LABOR DR | 2013-08-21 | — | — | CN | disclosed |
| CN-103038208-A | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | ESTEVE QUIMICA SA | 2013-04-10 | — | — | CN | disclosed |
| CN-102066333-A | 5-methyl-1-(naphthalen-2-yl)-1H-pyrazoles useful as sigma receptor inhibitors | ESTEVE LABOR DR | 2011-05-18 | — | — | CN | disclosed |