Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992432 | 0.83 | UTS2R (0.44) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL27992158 | 0.79 | MAPT (0.39) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL3333888 | 0.78 | DYRK1A (0.59) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL27992156 | 0.77 | DYRK1A (0.45) | ACHEMAPTTSHRTDP1HPGD | |
| SCHEMBL17517493 | 0.77 | DYRK1A (0.42) | UTS2RDYRK1AMAOAMCL1HASPIN | |
| SCHEMBL17517494 | 0.77 | DYRK1A (0.42) | UTS2RDYRK1AMAOAMCL1HASPIN | |
| SCHEMBL20097152 | 0.76 | ALKBH5 (0.59) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL17517548 | 0.75 | CYP1A2 (0.52) | ACHEDYRK1AMAOACYP1A2MCL1 | |
| SCHEMBL20340614 | 0.75 | DYRK1A (0.53) | DYRK1AMCL1HASPIN | |
| SCHEMBL22100020 | 0.74 | KDM4E (0.53) | ACHEBCHEMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177376-A | 1-Position diamine beta-carboline alkali compound, and preparation method, medicinal composition and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2014-12-03 | — | — | CN | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |