SCHEMBL20097152

SCHEMBL20097152

Cc1cccc2c3ccccc3n(C(C)C)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.59
FTO Q9C0B1 1/20 0.59
NPY5R Q15761 3/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
CDC25A P30304 1/20 0.45
CDC25C P30307 1/20 0.45
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
MAPT P10636 3/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
POLB P06746 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21561008 0.86 CDC25A (0.51) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL22600825 0.84 NPY5R (0.50) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL22336508 0.84 NR1I2 (0.49) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL26237868 0.83 BCHE (0.45) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL22336452 0.82 MEN1 (0.44) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL18376087 0.82 TDP1 (0.45) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL22336448 0.80 MAPT (0.61) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL23072091 0.80 BCHE (0.43) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL16640352 0.80 BCHE (0.43) ALKBH5FTONPY5RKMT2AMEN1
SCHEMBL20097041 0.80 BCHE (0.43) ALKBH5FTONPY5RKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-06 US disclosed
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-15 US disclosed
WO-2020162600-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-08-13 WO disclosed
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-08-29 US disclosed
WO-2018075947-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 ALKBH5 3438/4885FTO 4137/4885NPY5R 238/4885
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 ALKBH5 2298/4885FTO 268/4885NPY5R 4535/4885
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF L1CAM, LEF1, PIEZO1 ALKBH5 2908/4885FTO 416/4885NPY5R 4514/4885
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS POLRMT, EIF2AK2, NSUN3 ALKBH5 184/4885FTO 2321/4885NPY5R 4867/4885
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CRY2, NR2E3 ALKBH5 2348/4885FTO 1788/4885NPY5R 1766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.