Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901147 | 0.82 | PARP1 (0.52) | PARP1SLC22A12CASP6GAAVCAM1 | |
| SCHEMBL27918761 | 0.81 | SLC22A12 (0.37) | PARP1SLC22A12CASP6GAAVCAM1 | |
| SCHEMBL5408701 | 0.78 | CES1 (0.47) | GAATSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL10954211 | 0.72 | PARP1 (0.74) | PARP1CASP6VCAM1LMNATSHR | |
| SCHEMBL14934264 | 0.72 | PARP1 (0.52) | PARP1CASP6GAALMNAKMT2A | |
| SCHEMBL14934256 | 0.71 | PARP1 (0.51) | PARP1GAALMNAKMT2AALDH1A1 | |
| SCHEMBL8629267 | 0.71 | PARP1 (0.72) | PARP1CASP6GAAVCAM1LMNA | |
| SCHEMBL30995722 | 0.71 | PARP1 (0.72) | PARP1CASP6LMNATSHR | |
| SCHEMBL1766442 | 0.71 | PARP1 (0.72) | PARP1CASP6LMNATSHR | |
| SCHEMBL1767399 | 0.70 | PARP1 (0.70) | PARP1CASP6VCAM1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |