Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934225 | 0.81 | MEN1 (0.39) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL14934256 | 0.79 | PARP1 (0.51) | PARP1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10832502 | 0.78 | CA1 (0.49) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3390530 | 0.73 | MAPT (0.55) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL10954211 | 0.72 | PARP1 (0.74) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9672850 | 0.72 | MAPT (0.48) | GAAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL27918760 | 0.72 | PARP1 (0.52) | PARP1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8629267 | 0.71 | PARP1 (0.72) | PARP1GAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30995722 | 0.71 | PARP1 (0.72) | PARP1LMNACASP6 | |
| SCHEMBL1766442 | 0.71 | PARP1 (0.72) | PARP1LMNACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064029-A1 | BENZOYLUREA DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2013-05-10 | — | — | WO | disclosed |