Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901763 | 0.87 | CYP11B2 (0.38) | HTR2AHTR2CCYP11B1CYP11B2 | |
| SCHEMBL27901774 | 0.86 | DRD1 (0.36) | CYP11B1CYP11B2MAPT | |
| SCHEMBL27901809 | 0.84 | CYP11B2 (0.38) | HTR2AHTR2CCYP11B1CYP11B2MAPT | |
| SCHEMBL27919644 | 0.84 | DRD1 (0.38) | HTR2AHTR2CCYP11B1CYP11B2HTR2B | |
| SCHEMBL27919482 | 0.84 | HTR2C (0.39) | HTR2AHTR2CCYP11B1CYP11B2NOTUM | |
| SCHEMBL27901782 | 0.82 | MAPT (0.37) | HTR2AHTR2CCYP11B1CYP11B2KDM4C | |
| SCHEMBL27901762 | 0.82 | ESR1 (0.40) | HTR2AHTR2CCYP11B1CYP11B2 | |
| SCHEMBL27919500 | 0.81 | CYP11B2 (0.34) | HTR2AHTR2CCYP11B1CYP11B2HTR2B | |
| SCHEMBL27901787 | 0.80 | CYP11B2 (0.35) | CYP11B1CYP11B2NOTUM | |
| SCHEMBL27919512 | 0.79 | CYP17A1 (0.37) | CYP11B1CYP11B2KDM4CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108871-A | 17a-hydroxylase/c17,20-lyase inhibitors | NOVARTIS AG | 2013-05-15 | — | — | CN | claimed |
| CN-103108871-A | 17a-hydroxylase/c17,20-lyase inhibitors | NOVARTIS AG | 2013-05-15 | — | — | CN | disclosed |