Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901809 | 0.87 | CYP11B2 (0.38) | CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL27901762 | 0.86 | ESR1 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL27901761 | 0.86 | HTR2C (0.39) | CYP11B2CYP11B1CYP17A1NOTUMSCD | |
| SCHEMBL27919506 | 0.85 | CYP17A1 (0.45) | CYP17A1 | |
| SCHEMBL27901952 | 0.84 | CYP11B2 (0.37) | CYP11B2CYP11B1CYP17A1SCD | |
| SCHEMBL27919512 | 0.84 | CYP17A1 (0.37) | CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL27901782 | 0.82 | MAPT (0.37) | CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL27901763 | 0.81 | CYP11B2 (0.38) | CYP11B2CYP11B1 | |
| SCHEMBL27901774 | 0.80 | DRD1 (0.36) | CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL27919481 | 0.80 | HTR2A (0.36) | CYP11B2CYP11B1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108871-A | 17a-hydroxylase/c17,20-lyase inhibitors | NOVARTIS AG | 2013-05-15 | — | — | CN | disclosed |