Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3337412 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28932444 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6691301 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8917975 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL372448 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL919437 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3686169 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3683460 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28552920 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563499 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118315568-A | Cerium-doped lithium-rich manganese-based positive electrode material coated by nano cerium oxide and preparation method thereof | 中南大学 | 2024-07-09 | — | — | CN | claimed |
| CN-111994914-B | Ion co-doped beta-dicalcium silicate powder, preparation method and application | 苏州鼎安科技有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-112675804-B | Hydrated cerium carbonate dephosphorizing adsorbent and preparation method and application thereof | 哈尔滨工业大学 | 2022-08-23 | — | — | CN | claimed |
| CN-112675804-A | Hydrated cerium carbonate phosphorus removal adsorbent and preparation method and application thereof | 哈尔滨工业大学 | 2021-04-20 | — | — | CN | claimed |
| CN-111994914-A | Ion co-doped beta-dicalcium silicate powder, preparation method and application | 苏州鼎安科技有限公司 | 2020-11-27 | — | — | CN | claimed |
| US-10138561-B2 | Cerium citrate, method of making and corrosion inhibitor comprising cerium citrate | UNITED TECHNOLOGIES CORPORATION (US) | 2018-11-27 | — | — | US | claimed |
| EP-3257970-A1 | CERIUM CITRATE, METHOD OF MAKING AND CORROSION INHIBITOR COMPRISING CERIUM CITRATE | United Technologies Corporation (US) | 2017-12-20 | — | — | EP | claimed |
| US-20170350019-A1 | CERIUM CITRATE, METHOD OF MAKING AND CORROSION INHIBITOR COMPRISING CERIUM CITRATE | RTX CORPORATION | 2017-12-07 | — | — | US | claimed |
| CN-118315568-A | Cerium-doped lithium-rich manganese-based positive electrode material coated by nano cerium oxide and preparation method thereof | 中南大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-111994914-B | Ion co-doped beta-dicalcium silicate powder, preparation method and application | 苏州鼎安科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4269488-A2 | CERIUM CITRATE, METHOD OF MAKING AND CORROSION INHIBITOR COMPRISING CERIUM CITRATE | RTX Corporation (US) | 2023-11-01 | — | — | EP | disclosed |
| US-11780799-B2 | Cerium citrate, method of making and corrosion inhibitor comprising cerium citrate | RTX CORPORATION (US) | 2023-10-10 | — | — | US | disclosed |
| EP-3257970-B1 | CERIUM CITRATE, METHOD OF MAKING AND CORROSION INHIBITOR COMPRISING CERIUM CITRATE | RAYTHEON TECH CORP (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023108907-A1 | FUSED IRON CATALYST FOR PREPARING HIGH-CARBON α OLEFIN FROM SYNTHESIS GAS, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海兖矿能源科技研发有限公司 | 2023-06-22 | — | — | WO | disclosed |
| US-20070184965-A1 | Cerium-based oxide fiber and its fabricating method | NATIONAL TAIWAN UNIVERSITY | 2007-08-09 | — | — | US | disclosed |
| EP-0696936-B1 | DEHYDROGENATION CATALYST HAVING IMPROVED MOISTURE STABILITY, AND PROCESS FOR MAKING AND USING THE CATALYST | DOW CHEMICAL CO (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5510552-A | STEAMING ALKYL AROMATIC COMPOUND IN PRESENCE OF CALCINED CATALYST CONTAINING OXIDES OF IRON, POTASSIUM, CESIUM,CERIUM, AND HYDRAULIC CEMENT, ALSO WITH OXIDES FROM GROUPS 5, 6, 7, 8, 1B, 2B, AND/OR 3A | THE DOW CHEMICAL COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0696936-A1 | DEHYDROGENATION CATALYST HAVING IMPROVED MOISTURE STABILITY, AND PROCESS FOR MAKING AND USING THE CATALYST | DOW CHEMICAL CO (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5376613-A | Dehydrogenation catalyst and process for preparing same | THE DOW CHEMICAL COMPANY (US) | 1994-12-27 | — | — | US | disclosed |
| WO-1994025154-A1 | DEHYDROGENATION CATALYST HAVING IMPROVED MOISTURE STABILITY, AND PROCESS FOR MAKING AND USING THE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |