Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3337412 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2791985 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28932444 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6691301 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8917975 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL919437 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3686169 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3683460 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28552920 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563499 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122076451-A | Modified Ni/CeO2Preparation method and application of catalyst | — | 2026-05-26 | — | — | CN | claimed |
| EP-4744682-A1 | NOVEL CERIUM OXIDE NANOCOMPOSITE WITH ENHANCED BIOSTABILITY AND USE THEREOF | Cenyx Biotech Inc. (KR) | 2026-05-20 | — | — | EP | claimed |
| US-12458665-B2 | Cerium oxide nanocomposite and use thereof | CENYX BIOTECH INC. (KR) | 2025-11-04 | — | — | US | claimed |
| CN-117820088-B | Preparation method of m-ethylanisole | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| WO-2025014319-A1 | NOVEL CERIUM OXIDE NANOCOMPOSITE WITH ENHANCED BIOSTABILITY AND USE THEREOF | 주식회사 세닉스바이오테크 | 2025-01-16 | — | — | WO | claimed |
| CN-119040946-A | Self-supporting cerium doped spinel nanosheet electrocatalyst and preparation method and application thereof | 南京航空航天大学 | 2024-11-29 | — | — | CN | claimed |
| US-12077448-B2 | Ceria nanoparticles and ceria nanoparticles preparation method | Research & Business Foundation Sungkyunkwan University (KR) | 2024-09-03 | — | — | US | claimed |
| CN-118315568-A | Cerium-doped lithium-rich manganese-based positive electrode material coated by nano cerium oxide and preparation method thereof | 中南大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118022752-A | Preparation method and application of sub-nano level monodisperse copper cerium oxide catalyst | 北京工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117987865-A | Cerium doped ruthenium dioxide electrocatalyst and preparation method and application thereof | 海南大学 | 2024-05-07 | — | — | CN | claimed |
| US-20130108526-A1 | METHOD FOR MATERIALS RECOVERY FROM CATALYSTS COMPRISING IRON, CERIUM, MOLYBDENUM, AND POTASSIUM | BASF SE (DE) | 2013-05-02 | — | — | US | claimed |
| US-20120049181-A1 | COMPOSITION FOR OXIDE THIN FILM, METHOD OF PREPARING THE COMPOSITION, METHOD OF FORMING THE OXIDE THIN FILM, AND ELECTRONIC DEVICE USING THE COMPOSITION | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2012-03-01 | — | — | US | claimed |
| US-7867463-B2 | Process for producing cerium oxide nanocrystals | INSTITUTE FOR BASIC SCIENCE (KR) | 2011-01-11 | — | — | US | claimed |
| US-7811545-B2 | Reacting a metal salt dissolved in water with an alkali metal salt of a carboxylic acid dissolved in a first hydrdocarbon solvent to form a metal carboxylate complex; heating the metal carboxylate complex dissolved in a second solvent of ethers to produce the highly crystalline nanoparticles | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2010-10-12 | — | — | US | claimed |
| US-7431758-B2 | Cerium oxide particles and production method therefor | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-10-07 | — | — | US | claimed |
| EP-1945569-A1 | PROCESS FOR PRODUCING CERIUM OXIDE NANOCRYSTALS | Seoul National University Industry Foundation (KR) | 2008-07-23 | — | — | EP | claimed |
| US-20070092423-A1 | Process for producing cerium oxide nanocrystals | INSTITUTE FOR BASIC SCIENCE (KR) | 2007-04-26 | — | — | US | claimed |
| WO-2007043774-A1 | PROCESS FOR PRODUCING CERIUM OXIDE NANOCRYSTALS | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-04-19 | — | — | WO | claimed |
| US-20060150526-A1 | Cerium oxide particles and process for the production therefor | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-07-13 | — | — | US | claimed |
| US-20060032147-A1 | Method of preparing slurry composition for chemical mechanical polishing | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458665-B2 | Cerium oxide nanocomposite and use thereof | CD59, CLN6, CERS2 | CA4 306/4885CA1 300/4885FAHD1 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.