Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2791985 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28932444 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6691301 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8917975 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL372448 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL919437 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3686169 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3683460 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28552920 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563499 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118637820-B | Water-retaining rare earth composite ceramic glaze and preparation method and application thereof | 天津包钢稀土研究院有限责任公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118637820-A | Water-retaining rare earth composite ceramic glaze and preparation method and application thereof | 天津包钢稀土研究院有限责任公司 | 2024-09-13 | — | — | CN | claimed |
| CN-115159558-B | Precipitation method of rare earth carbonate | 冕宁县新盛源新材料科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-115159558-A | Precipitation method of rare earth carbonate | 冕宁县新盛源新材料科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| US-12492478-B2 | Coated and plated steel sheet or coated and plated steel strip | NIPPON STEEL CORPORATION (JP) | 2025-12-09 | — | — | US | disclosed |
| US-20250353756-A1 | METHODS OF INCREASING THE RATE OF PHASE CONVERSION AND USE OF CARBOXYLATE-CONTAINING SUBSTANCES | Baotou Research Institute of Rare Earths (CN) | 2025-11-20 | — | — | US | disclosed |
| CN-119976929-A | Preparation method of cerium oxide nanorod, cerium oxide nanorod and application thereof | 万华化学集团股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| US-12281254-B2 | Alumina-based thermally conductive oxide and method for producing same | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2025-04-22 | — | — | US | disclosed |
| CN-118637820-B | Water-retaining rare earth composite ceramic glaze and preparation method and application thereof | 天津包钢稀土研究院有限责任公司 | 2024-12-06 | — | — | CN | disclosed |
| EP-4431640-A1 | SOLID POLYMER-TYPE WATER ELECTROLYSIS MEMBRANE-ELECTRODE JOINT BODY AND WATER ELECTROLYSIS DEVICE | AGC INC. (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118637820-A | Water-retaining rare earth composite ceramic glaze and preparation method and application thereof | 天津包钢稀土研究院有限责任公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118529767-A | Method for increasing the rate of phase inversion and use of carboxylate-containing materials | 包头稀土研究院 | 2024-08-23 | — | — | CN | disclosed |
| EP-2039415-A1 | DEHUMIDIFYING/DEOXIDIZING AGENT | Mitsui Mining and Smelting Co., Ltd (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-1803686-B1 | Cerium-zirconium mixed oxide and method for manufacturing the same | DAIICHI KIGENSOKAGAKU KOGYO CO (JP) | 2009-03-04 | — | — | EP | disclosed |
| EP-1803686-A1 | Cerium-zirconium mixed oxide and method for manufacturing the same | Daiichi Kigenso Kagaku Co., Ltd. (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070148072-A1 | Cerium-zirconium mixed oxide and method for manufacturing the same | DAIICHI KIGENSO KAGAKU KOGYO CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-0865412-B1 | CERIUM OXIDE WITH PORES HAVING A LAMELLAR STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF IN CATALYSIS | RHODIA CHIMIE SA (FR) | 2003-09-03 | — | — | EP | disclosed |
| US-5994260-A | CATALYTIC EXHAUST SYSTEM | RHODIA CHIMIE (FR) | 1999-11-30 | — | — | US | disclosed |
| EP-0865412-A1 | CERIUM OXIDE WITH PORES HAVING A LAMELLAR STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF IN CATALYSIS | RHODIA CHIMIE (FR) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020772-A1 | CERIUM OXIDE WITH PORES HAVING A LAMELLAR STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF IN CATALYSIS | RHODIA CHIMIE (FR) | 1997-06-12 | — | — | WO | disclosed |