Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.67 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | CDC7 | O00311 | 6/20 | 0.65 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974859 | 0.82 | CDC7 (0.84) | KDM4EALDH1A1CDC7DBF4SMN1; SMN2 | |
| SCHEMBL16113884 | 0.79 | CDC7 (1.00) | KDM4EALDH1A1CDC7DBF4SMN1; SMN2 | |
| SCHEMBL289704 | 0.77 | KDM4E (0.79) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL14148666 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL5528298 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL14148653 | 0.75 | CDC7 (0.61) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL975863 | 0.75 | CDC7 (0.68) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL4485015 | 0.75 | CDC7 (0.71) | KDM4EALDH1A1CDC7DBF4SMN1; SMN2 | |
| SCHEMBL8823109 | 0.73 | CDC7 (0.61) | KDM4EALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL8823093 | 0.73 | SMN1; SMN2 (0.63) | KDM4EALDH1A1CDC7DBF4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333134-A | 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound, composition as well as preparation methods and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-10-02 | — | — | CN | claimed |
| CN-103333134-B | 2-(3-cyano group-4-alkoxyl group) phenyl-4-substituted thiazole-5-formic acid compound, composition and method of making the same and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103333134-A | 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound, composition as well as preparation methods and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-10-02 | — | — | CN | disclosed |