Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920108 | 0.76 | LMNA (0.38) | LMNATSHRCTSAALDH1A1 | |
| SCHEMBL10520837 | 0.75 | IDO1 (0.39) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL6680507 | 0.71 | IDO1 (0.41) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL3832812 | 0.69 | CTSA (0.39) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL24369516 | 0.68 | TAAR1 (0.49) | SLC6A2SLC6A4CYP2D6SLC6A3KCNH2 | |
| SCHEMBL1561689 | 0.65 | TSHR (0.48) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL31068750 | 0.64 | TAAR1 (0.43) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL25258421 | 0.64 | TAAR1 (0.43) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL3141582 | 0.64 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3IDO1TDO2 | |
| SCHEMBL31175995 | 0.64 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333194-A | Silicic acid-3-(3-bromophenyl)-chloropropyl ethyl ester compound used as fire retardant and preparation method thereof | USTC UNIV SCIENCE TECH CN | 2013-10-02 | — | — | CN | disclosed |
| CN-103333194-A | Silicic acid-3-(3-bromophenyl)-chloropropyl ethyl ester compound used as fire retardant and preparation method thereof | USTC UNIV SCIENCE TECH CN | 2013-10-02 | — | — | CN | disclosed |