Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407170 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP2D6HPGD | |
| SCHEMBL10520837 | 0.78 | IDO1 (0.39) | ALDH1A1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27920108 | 0.77 | LMNA (0.38) | CTSAALDH1A1SLC6A9 | |
| SCHEMBL3825678 | 0.75 | KDM4E (0.50) | ALDH1A1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6680507 | 0.74 | IDO1 (0.41) | CTSAALDH1A1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL24369516 | 0.74 | TAAR1 (0.49) | ALDH1A1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27633524 | 0.72 | L3MBTL1 (0.49) | CTSACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27633523 | 0.72 | L3MBTL1 (0.49) | CTSACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15427663 | 0.72 | ALDH1A1 (0.44) | CTSAALDH1A1GAAHSD17B3HPGD | |
| SCHEMBL11254513 | 0.71 | CTSA (0.49) | CTSAALDH1A1SLC6A9GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099760-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068268-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | disclosed |