Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203875 | 0.83 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL16212418 | 0.81 | KDM4E (0.66) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL19222365 | 0.77 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL23488102 | 0.75 | KDM4E (0.80) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL14777184 | 0.74 | NPC1 (0.54) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL24933006 | 0.70 | KDM4E (0.51) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL20219598 | 0.70 | NPC1 (0.52) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL17694678 | 0.70 | KDM4E (0.78) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL14352777 | 0.70 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL23488101 | 0.69 | KDM4E (1.00) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | claimed |
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | disclosed |