Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27922135 | 1.00 | OPRM1 (0.52) | OPRM1OPRK1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL4848198 | 0.91 | KMT2A (0.60) | KMT2AL3MBTL1ROCK2CCR2NPC1 | |
| SCHEMBL26502013 | 0.91 | KMT2A (0.60) | KMT2AL3MBTL1ROCK2CCR2NPC1 | |
| SCHEMBL5412662 | 0.90 | KMT2A (0.64) | OPRM1OPRK1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL6128768 | 0.90 | KMT2A (0.64) | OPRM1OPRK1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL554777 | 0.90 | KMT2A (0.64) | OPRM1OPRK1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL13088854 | 0.89 | KDM4E (0.53) | KMT2AL3MBTL1ROCK2CCR2 | |
| SCHEMBL555720 | 0.86 | KMT2A (0.62) | KMT2AL3MBTL1CCR2DRD2DRD4 | |
| SCHEMBL28966343 | 0.86 | DRD2 (0.50) | KMT2AL3MBTL1ROCK2CA1CA2 | |
| SCHEMBL28966341 | 0.86 | DRD2 (0.50) | KMT2AL3MBTL1ROCK2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373953-A | Preparation method for 3-aminopiperidine and optical isomer thereof | SHANGHAI SUN SAIL PHARMACEUTICAL SCIENCE & TECHNOLOGY CO LTD | 2013-10-30 | — | — | CN | disclosed |