Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635159 | 0.86 | ALDH1A1 (0.64) | GAAHSD17B10ALDH1A1TP53RAB9A | |
| SCHEMBL5179768 | 0.83 | MAPT (0.75) | GAAALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19277750 | 0.83 | GAA (1.00) | GAAALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL9453941 | 0.82 | MEN1 (0.77) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30557461 | 0.82 | MEN1 (0.77) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10189852 | 0.81 | GAA (0.73) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30703669 | 0.81 | HSD17B10 (1.00) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12133 | 0.81 | HSD17B10 (1.00) | GAAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28807981 | 0.80 | SMN1; SMN2 (0.66) | GAAHSD17B10ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL21973103 | 0.79 | ALDH1A1 (0.65) | GAAALDH1A1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373969-A | Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same | SHANGHAI INST ORGANIC CHEM | 2013-10-30 | — | — | CN | disclosed |