Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.66 |
| ▸ | MC5R | P33032 | 2/20 | 0.65 |
| ▸ | MC1R | Q01726 | 2/20 | 0.65 |
| ▸ | ECE1 | P42892 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | BRS3 | P32247 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901464 | 1.00 | KCNT1 (0.66) | KCNT1MC5RMC1RECE1KDM4E | |
| Trifluoroacetic Acid SCHEMBL13723646 | 0.93 | KCNT1 (0.59) | KCNT1MC5RMC1RECE1MAPT | |
| Trifluoroacetic Acid SCHEMBL27959205 | 0.93 | KCNT1 (0.59) | KCNT1MC5RMC1RECE1MAPT | |
| Trifluoroacetic Acid SCHEMBL27941817 | 0.91 | KCNT1 (0.57) | KCNT1MC5RMC1RECE1KDM4E | |
| Trifluoroacetic Acid SCHEMBL15284580 | 0.91 | KCNT1 (0.57) | KCNT1MC5RMC1RECE1KDM4E | |
| SCHEMBL29810269 | 0.90 | KCNT1 (0.69) | KCNT1KDM4EMEN1LMNAMPO | |
| SCHEMBL9583736 | 0.90 | KCNT1 (0.69) | KCNT1KDM4EMEN1LMNAMPO | |
| SCHEMBL8705016 | 0.90 | KCNT1 (0.69) | KCNT1KDM4EMEN1LMNAMPO | |
| SCHEMBL900917 | 0.90 | KCNT1 (0.69) | KCNT1KDM4EMEN1LMNAMPO | |
| SCHEMBL29459408 | 0.86 | MC5R (0.84) | KCNT1MC5RMC1RECE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103379912-B | Positive carboxyalkyl ear statin and application thereof | SEATTLE GENETICS, INC. (US) | 2016-03-16 | — | — | CN | disclosed |
| CN-104254342-A | FGRF antibody drug conjugates (ADCs) and the use thereof | SEATTLE GENETICS INC | 2014-12-31 | — | — | CN | disclosed |
| CN-103379912-A | N-carboxyalkyl auristatins and the use thereof | SEATTLE GENETICS INC | 2013-10-30 | — | — | CN | disclosed |