Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810269 | 1.00 | KCNT1 (0.69) | KCNT1ALOX15ACEKMT2ASMN1; SMN2 | |
| SCHEMBL9583736 | 1.00 | KCNT1 (0.69) | KCNT1ALOX15ACEKMT2ASMN1; SMN2 | |
| SCHEMBL900917 | 1.00 | KCNT1 (0.69) | KCNT1ALOX15ACEKMT2ASMN1; SMN2 | |
| SCHEMBL150050 | 0.92 | ALOX15 (0.65) | ALOX15ACEKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22654181 | 0.92 | ALOX15 (0.65) | ALOX15ACEKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29773000 | 0.92 | ALOX15 (0.65) | ALOX15ACEKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9805977 | 0.92 | KCNT1 (0.62) | KCNT1ALOX15ACEKMT2AITGB2 | |
| SCHEMBL11346003 | 0.92 | KCNT1 (0.62) | KCNT1ALOX15ACEKMT2AITGB2 | |
| SCHEMBL901464 | 0.90 | KCNT1 (0.66) | KCNT1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL27923213 | 0.90 | KCNT1 (0.66) | KCNT1KMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466313-B | 1-Imidazole-beta-carboline-3-formyl-LDV, preparation, anticancer metastasis activity and application | 首都医科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-115466250-B | 6-Aminocaproyl tryptophan benzyl ester modified oxo-oxazolidines, synthesis, activity and application thereof | 首都医科大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-113754720-B | Synthesis, biological activity and application of dimethyl dioxane-tetrahydro-beta-carboline-3-formyl-RGDF | 首都医科大学 | 2024-04-23 | — | — | CN | disclosed |
| CN-113754725-B | Synthesis, biological activity and application of dimethyl dioxane-tetrahydro-beta-carboline-3-formyl-RGDV | 首都医科大学 | 2024-04-23 | — | — | CN | disclosed |
| CN-115477656-B | Dioxahexacyclic-tetrahydrocarboline-3-formylamino acid targeting P-selectin, preparation and application | 首都医科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115477655-B | Preparation and application of dioxane-tetrahydrocarboline-3-formylamino acid in butt joint with tumor necrosis factor-alpha | 首都医科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-113754724-B | Synthesis, biological activity and application of dimethyl dioxane-tetrahydro-beta-carboline-3-formyl-RGDS | 首都医科大学 | 2023-12-19 | — | — | CN | disclosed |
| US-11185100-B2 | Methods for modulating taste receptors | MARS, INCORPORATED (US) | 2021-11-30 | — | — | US | disclosed |
| EP-3229610-B1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS INC (US) | 2021-06-09 | — | — | EP | disclosed |
| CN-110294740-A | A kind of N- benzyl amino acid water solubility couroupitine A and its preparation method and application | 同济大学 | 2019-10-01 | — | — | CN | disclosed |
| US-20180168208-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2018-06-21 | — | — | US | disclosed |
| US-20180168208-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2018-06-21 | — | — | US | disclosed |
| US-5834433-A | ANTITUMOR AND -CARCINOMA AGENTS; SMALL CELL LUNG AND PROSTATIC CARCINOMA; ANTIMIOTIC AND ANTISECRETORY AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0468497-A2 | Peptide-antagonists of bombesin/GRP | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0434979-A1 | Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| CN-1051914-A | The peptide class | MERRELL DOW PHARMA | 1991-06-05 | — | — | CN | disclosed |
| EP-0145304-A1 | Tetrahydro-beta-carboline derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |