SCHEMBL27925528

SCHEMBL27925528

CC(=O)c1ccc(C(=O)c2ccccc2)c(O)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.64
MAPK1 P28482 4/20 0.64
KDM4E B2RXH2 4/20 0.64
HSD17B10 Q99714 3/20 0.64
ALOX15 P16050 1/20 0.64
BCL2 P10415 1/20 0.53
MCL1 Q07820 1/20 0.53
GAA P10253 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
KMT2A Q03164 1/20 0.52
KEAP1 Q14145 1/20 0.52
NFE2L2 Q16236 1/20 0.52
ALDH1A1 P00352 3/20 0.50
AKR1C3 P42330 1/20 0.50
LMNA P02545 4/20 0.49
HPGD P15428 3/20 0.49
HTT P42858 2/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069965 0.89 MAPT (0.69) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL28687922 0.82 KDM4E (0.62) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL27409331 0.82 MAPT (0.53) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL27811794 0.82 HDAC1 (0.66) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL29366285 0.82 HDAC1 (0.66) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL93423 0.82 HDAC1 (0.66) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL822891 0.81 AKR1C3 (0.68) MAPTHSD17B10GAAKMT2AALDH1A1
Benzophenone SCHEMBL28066611 0.80 HDAC1 (0.63) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL28121439 0.79 MAPT (0.58) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL27438560 0.79 KMT2A (0.66) MAPTMAPK1KDM4EHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103124551-A Composition for cosmetic treatment containing extract of muscipula QUANTUM PHARMACEUTICALS LTD 2013-05-29 CN disclosed