Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205287 | 0.89 | AKR1B1 (0.48) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL27529220 | 0.88 | AKR1B1 (0.47) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL27812907 | 0.87 | TYMS (0.62) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL27925894 | 0.85 | AKR1B1 (0.47) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL30584152 | 0.85 | AKR1B1 (0.47) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL30350193 | 0.85 | AKR1B1 (0.51) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL27519163 | 0.85 | AKR1B1 (0.51) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL30447066 | 0.84 | AKR1B1 (0.53) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL30960823 | 0.78 | TYMS (0.75) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL27983477 | 0.75 | AKR1B1 (0.49) | AKR1B1HSD17B10KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |