Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726593 | 0.79 | TSHR (0.55) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 | |
| SCHEMBL7374833 | 0.73 | TAAR1 (0.42) | TDP1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9698029 | 0.71 | TSHR (0.47) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 | |
| SCHEMBL7375842 | 0.71 | PARP1 (0.38) | TSHRKMT2APARP1LMNA | |
| SCHEMBL9168108 | 0.71 | CYP1A2 (0.43) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL10586812 | 0.70 | TSHR (0.53) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL11413912 | 0.70 | TSHR (0.53) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 | |
| SCHEMBL9357557 | 0.70 | TSHR (0.39) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 | |
| SCHEMBL24199108 | 0.69 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 | |
| SCHEMBL331655 | 0.69 | TSHR (0.52) | ALDH1A1TSHRHSD17B10TDP1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |