Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413912 | 0.85 | TSHR (0.53) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL10586812 | 0.85 | TSHR (0.53) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL11230595 | 0.83 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL698195 | 0.83 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3922686 | 0.83 | TSHR (0.57) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL24199108 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL4313800 | 0.83 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL22124430 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6546793 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6576001 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562837-B2 | Preparation of phenyl compounds | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562837-B2 | Preparation of phenyl compounds | FDPS, DHPS, DDT | TSHR 4645/4885ALDH1A1 860/4885HSD17B10 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.