Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2700536 | 0.86 | ALDH1A1 (0.37) | NAAAALDH1A1CYP1A2CES2EPHX1 | |
| SCHEMBL2249573 | 0.79 | EPHX2 (0.50) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL3294299 | 0.78 | EPHX2 (0.49) | NAAAEPHX2ALDH1A1 | |
| SCHEMBL5710073 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL21569213 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL6049453 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL7561339 | 0.78 | TSHR (0.44) | NAAAEPHX2CA12CA1CA2 | |
| SCHEMBL30977763 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL26846117 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 | |
| SCHEMBL2059827 | 0.78 | NAAA (0.51) | NAAAEPHX2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796058-B | Compound having thrombopoietin receptor agonism | SHIONOGI & CO | 2015-05-13 | — | — | CN | disclosed |
| CN-103130739-A | Compounds having thrombopoietin receptor agonism | SHIONOGI & CO | 2013-06-05 | — | — | CN | disclosed |