SCHEMBL279268

SCHEMBL279268

CCOC(C)Oc1ccc(N(c2ccc(CC)cc2)c2ccc(-c3ccc(N(c4ccc(CC)cc4)c4ccc(OC(C)OCC)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
MAPT P10636 2/20 0.34
EGFR P00533 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP2C19 P33261 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
CNR2 P34972 1/20 0.31
TSPO P30536 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279481 1.00 PPARG (0.35) PPARGPPARAMAPTEGFRLMNA
SCHEMBL14063434 0.96 PPARG (0.33) PPARGPPARAMAPTEGFR
SCHEMBL9608753 0.93 PPARG (0.35) PPARGPPARAMAPTEGFRCYP2C19
SCHEMBL279014 0.92 LMNA (0.38) MAPTLMNACYP2C19CYP1A2CYP2C9
SCHEMBL279470 0.87 LMNA (0.42) MAPTLMNAL3MBTL1POLBCNR2
SCHEMBL5701335 0.87 PPARA (0.42) PPARGPPARAMAPTLMNATSHR
SCHEMBL12891472 0.85 CYP1A2 (0.34) MAPTLMNACYP2C19CYP1A2CYP2C9
SCHEMBL4059616 0.83 LMNA (0.46) PPARGPPARAMAPTLMNACYP2C19
SCHEMBL279167 0.81 L3MBTL1 (0.38) PPARGPPARAMAPTLMNAATM
SCHEMBL279565 0.81 L3MBTL1 (0.38) PPARGPPARAMAPTLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed