Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817063 | 0.78 | CNR2 (0.66) | RAD52CNR1CNR2ABCB1PTGS1 | |
| SCHEMBL12480314 | 0.78 | PTGS2 (0.47) | CNR1CNR2ABCB1PTGS1PTGS2 | |
| SCHEMBL12480026 | 0.77 | ABCB1 (0.64) | ABCB1PTGS1PTGS2PLA2G2ALMNA | |
| SCHEMBL27927349 | 0.73 | RAD52 (0.42) | RAD52HDAC6MAPTHTTCFD | |
| SCHEMBL3088444 | 0.73 | MAPT (0.50) | POLBHDAC6LMNAMAPTHTT | |
| SCHEMBL27721422 | 0.73 | IL1R1 (0.47) | CNR1CNR2POLBABCB1PTGS1 | |
| Hydrochloric Acid SCHEMBL28531727 | 0.71 | MAPT (0.49) | POLBHDAC6LMNAMAPTHTT | |
| SCHEMBL14560446 | 0.71 | RAD52 (0.49) | RAD52KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL27935661 | 0.70 | IL1R1 (0.44) | CNR1CNR2POLBABCB1PTGS1 | |
| SCHEMBL27927320 | 0.70 | POLB (0.41) | POLBLMNAMAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402996-A | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD) | NOVARTIS AG | 2013-11-20 | — | — | CN | disclosed |